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The sequencing data from 10x Genomics Chromium Single Cell CNV Solution for patient S0 are available at -cell-dna/datasets. Raw read counts and phased SNP counts for patient S0 are available at and for patient S1 at The DOP-PCR sequencing data of 89 breast tumor cells are available from the NCBI Sequence Read Archive under accession SRA: SRP114962. All the processed data for all datasets of patients S0 and S1 and for the DOP-PCR data, as well as all the results of CHISEL, are available on GitHub at -group/chisel-data.



The bevel is ground sharp at 30º, but a higher secondary bevel of around 35º is advisable, depending on the wood and how the chisel is being used. On very hard woods, like oak, hard maple or exotic species, take lighter cuts and use a higher secondary bevel. Additional honing is recommended. You can find sharpening instructions in a printable PDF format here: Sharpening Instructions PDF.

"tool with a beveled or sloping cutting edge at one end, used for paring, splitting, gouging, or cutting out," early 14c., from Anglo-French cisel, Old French cisel "chisel," in plural, "scissors, shears" (12c., Modern French ciseau), from Vulgar Latin *cisellum "cutting tool," from Latin caesellum, diminutive of caesus, past participle of caedere "to cut" (from PIE root *kae-id- "to strike"). Related: Chiseled; chiseling.

c. 1500, "to break, cut, gouge, etc. with a chisel," from chisel (n.). Slang sense of "to cheat, defraud" is first recorded in 1808 as chizzel; origin and connection to the older word are obscure (but compare slang sense of gouge; perhaps the sense is "to cut close" as in a bargain). Related: Chiseled; chiseling.

mid-14c., "chisel with a concave blade," from Old French gouge "a gouge" (14c.), from Late Latin gubia, alteration of gulbia "hollow beveled chisel," probably from Gaulish (compare Old Irish gulban "prick, prickle," Welsh gylfin "beak"). Meaning "an imposition, a cheat" is from 1845, American English colloquial.

I feel like this card creates a really interesting set of questions to answer: Is this ice worth chiseling? Should the Corp spend his turn clearing virus counters if chisel is installed on an expensive piece of ice?

With this in mind, one of the keys of this card would be placing the Corp in a situation where cleaning the virus counters or leaving the counters be will both result in a situation that is pretty annoying for them the corp. How this can be achieved, well, I am a bit of a noobie so I don't know a good answer to that. Maybe threatening multiple servers, one with chisel and one with other resources, will be the best way for using this card.

Chisel just got a whole lot better with the addition of Devil Charm in Uprising. No more waiting around for counters to built up! -6 strength deals with most ICE and with Simulchip you can recur your Chisel as well. Thankfully Devil Charm can't be recurred. The question of the corp purging virus counters as a counterplay comes up very rarely in my experience, as you want to get the ICE destroyed as soon as you lay down the chisel (using multiple runs, if necessary).

This chisel was clearly made for use and looks as if it has indeed been used. It was found in a tomb that contained at least six burials but no object of demonstrably post-Mentuhotep II date. There was even a piece of linen marked for Mentuhotep II's wife Queen Neferu. The mark incised into the chisel was previously understood to represent the pyramid which Museum excavator Herbert E. Winlock and others thought had originally existed above the solid core structure of the temple of Mentuhotep II at Deir el-Bahri. The existence of this pyramid has been put into doubt, however, although renewed discussions are under way. The mark also occurs on linen sheets from the tomb of the "Slain Soldiers" (MMA 507 see here 27.3.84-134), which has been shown to be of the time of Senwosret I, and on another piece of linen found at Lisht South close to the pyramid of that king. The sign can, therefore, no longer be exclusively associated with the temple of Mentuhotep II at Deir el-Bahri, even if this particular chisel was made and used during that king's reign. The mark's form and purpose remain enigmatic.

Start recesses or mortises by outlining the area with a sharp utility knife or by making a series of shallow chisel cuts perpendicular to the surface. Skip this step and you risk chipping wood outside the mortise. Then remove thin slices by tapping the chisel with a hammer, bevel side down as in Photo 1, to carve out the wood inside the perimeter.

Chop out large Amounts of wood by slicing off small amounts with each cut. Strike the chisel with a hammer and chop down about 1/2 in. Then chisel from the end to remove the piece before continuing. Your chisel must be sharp for this cut.

Chisel out dadoes and other more precise joints a little at a time with a series of shallow cuts rather than driving the chisel too deep (Photo 4). Use a hammer or mallet for rough work or press with the heel of your hand for lighter cutting chores or finer cuts.

Scrape glue joints or other imperfections from wood projects by holding the blade at a right angle to the wood with the back of the chisel facing you. To remove thin shavings, support the blade with your fingers and press down while you draw the chisel toward you.

Next, polish the back of the chisel by rubbing it back and forth over progressively finer wet/dry sandpaper, pressing the back perfectly flat to the paper. For all sharpening, a good progression of paper is 120, 220, 400 and 600 grit.

Built with two rows of double mounted 24-inch (61 cm) concave razor blade disks and four ranks of 1400-pound (635 kg) trips with on-edge chisel shanks, the 483 Chisel Pro gives the soil mixing of a ripper and the width of a chisel plow. Sixty-inch (152 cm) spacing between shanks on each of the ranks allows for excellent trashflow through the tool. The overall 15-inch (38 cm) spacing aids in a smoother field than the typical wider shank spacing of disk rippers. 041b061a72

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